What begins as withdrawing from friends and activities and a loss of interest in work can escalate to harming oneself. In clinical trials and public use, there have been cases where antidepressant users have thought about, attempted or committed suicide.
Antidepressants have also been shown to have other dangerous side effects, including severe birth defects when a woman takes the drug during pregnancy. In fact, dozens of women who took antidepressants during pregnancy have filed lawsuits after their children suffered birth defects.
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http://www.drugwatch.com/ssri/suicide/